A SYMPOSIUM IN HONOR OF THE
80+ Birthday of Joachim Frank:
In Celebration of his Contributions to Cryo-EM and
Ribosome Structure, Dynamics and Function
Sunday, September 4, 2022 | 8:00 AM-7:00 PM | Vagelos Education Center, Columbia University Medical Center New York, NY
(just before the 2022 CSHL Translational Control Meeting)
ABOUT
In honor of Joachim’s 80+ birthday, we invite you to join us for an all-day symposium of special speakers and presentations followed by a reception.
PROGRAM
8:00 - 9:00
Registration and Light Breakfast
CRYO-EM: PAST, PRESENT, AND FUTURE 1
9:00 - 9:10
Chair: David DeRosier
Brandeis University
9:10 - 9:30
Yifan Cheng
University of California at San Francisco/HHMI
Single-particle cryo-EM of membrane proteins
9:30 - 9:50
Mikel Valle
Center for Cooperative Research in Biosciences in Bilbao
Exploring multi-pathway enzymatic reactions by cryo-EM
9:50 - 10:10
José María Carazo
National Center for Biotechnology, CNB-CSIC, Madrid
The flexibility of biological macromolecules as revealed by cryo-EM
10:10 - 10:30
Elizabeth Villa
University of California in San Diego/HHMI
Opening windows into the cell: Bringing structure to cell biology using
cryo-electron tomography
10:30 - 10:55
Coffee Break
THE RIBOSOME AND TRANSLATION 1
10:55 - 11:00
Chair: Christian Spahn
Charité, Berlin University of Medicine
11:00 - 11:20
Peter Moore
Yale University
On ribosomes and microscopes
11:20 - 11:40
Christopher Hellen
SUNY Downstate Health Sciences University
The mechanism of initiation on the encephalomyocarditis virus IRES
11:40 - 12:00
Måns Ehrenberg
Uppsala University
RF3 action: A delicate truth
12:00 - 12:20
Yaser Hashem
University of Bordeaux
Alterations in mRNA translation initiation in colorectal cancer
12:20 - 12:40
Group Picture
12:40 - 1:40
Lunch
CRYO-EM: PAST, PRESENT, AND FUTURE 2
1:40 - 1:45
Chair: Robert Grassucci
Columbia University
1:45 - 2:05
Eva Nogales
University of California at Berkeley/HHMI
Overcoming sample preparation issues in cryo-EM
2:05 - 2:25
Karissa Sanbonmatsu
Los Alamos National Laboratory
Integrating cryo-EM, single molecule FRET and molecular simulation
to elucidate the structural dynamics of the ribosome
2:25 - 2:45
John Rubinstein
The Hospital for Sick Children, Toronto
Ab initio: single particle cryoEM of the ATP synthase
2:45 - 3:05
Bridget Carragher
Simons Electron Microscopy Center, New York Structural Biology Center
Time-resolved single particle EM
3:05 - 3:30
Coffee Break
THE RIBOSOME AND TRANSLATION 2
3:30 - 3:35
Chair: Christopher Hellen
State University of New York, Downstate Health Sciences
3:35 - 3:55
Amédée des Georges
City University of New York
Structure of DHX29 bound to the pre-initiation complex sheds light
on its mRNA unwinding mechanism
3:55 - 4:15
Suparna Sanyal
Uppsala University
Cryo-EM complements biochemistry to decipher the mechanism of
action of two antibiotics
4:15 - 4:35
Jeffrey Kieft
University of Colorado Anschutz Medical Campus
Structured viral RNAs that manipulate translation machinery
4:35 - 4:55
Rachel Green
Johns Hopkins University/HHMI
Colliding ribosomes function as a signaling hub for promoting diverse
cell fate decisions
CONCLUDING REMARKS
4:55 - 5:15
Joachim Frank
Columbia University
5:15 - 6:30
Reception
SPONSORS
